News & Publications – Pittsburgh Pharmacogenomics

2026

2026 | Mar 2

Genetic Testing for APOL1 in Adults With Hypertension: The GUARDD-US Randomized Clinical Trial

Eadon MT, Cavanaugh KL, She L, Steen-Burrell KA, Mohottige D, Nadkarni GN, Kitzman H, Chakraborty H, Empey PE, Limdi NA, Singh R, Beasley CM, Parker AS, Cicali EJ, Ramos MA, Clermont S, Dodgen L, Elwood EN, Robinson M, Umeukeje EM, Garcia Ortega A, Shroff N, Rosenman MB, Nguyen KA, Volpi S, Rider R, Dexter PR, Skaar TC, Peterson JF, Cavallari LH, Johnson JA, Wyatt CM, Orlando LA, Cooper-DeHoff RM, Horowitz CR.

JAMA Netw Open. 2026 Mar 2;9(3):e260528. doi: 10.1001/jamanetworkopen.2026.0528. PMID: 41784962.

2026 | Jan 31

ABCD-GENE score and bleeding in post-PCI patients: Implications for guided de-escalation of antiplatelet therapy

Coons JC, Polkowski K, Prebehalla L, Smith AC, Empey PE.

J Cardiovasc Pharmacol Ther. 2026 Jan-Dec;31:10742484261457268. doi: 10.1177/10742484261457268. Epub 2026 Jun 2. PMID: 42227816.

2026 | Jan 10

Automated extraction of fluoropyrimidine treatment and treatment-related toxicities from clinical notes using natural language processing

Wu X, Kreider MS, Empey PE, Li C, Wang Y.

Int J Med Inform. 2026 Jan 10;209:106276. DOI: 10.1016/j.ijmedinf.2026.106276. PMID: 41534241.

2025

2025 | Sep 5

Pharmacogenomics of buprenorphine – a narrative review

Aravindan L, Velu S, Sivam I, Sivam S, Tallapaneni PS, Ressler R, Marks M, Venkataramanan R, Radhakrishnan R, Sadhasivam S.

Pharmacogenomics. 2025 May-Jun;26(7-9):263-270. DOI: 10.1080/14622416.2025.2546770. PMID: 40908813.

2025 | Aug 25

Understanding clinician preferences to support pharmacogenomic results in electronic health records: A qualitative study in an academic health system.

Dreikorn EN, Sacchi S, Riden K, Empey PE, Massart MB, Berenbrok LA.

J Am Pharm Assoc (2003). 2025 Aug 25:102912. DOI: 10.1016/j.japh.2025.102912. PMID: 40865680.

2025 | Jul 12

Towards an integrated resource for pharmacogenomics (PGx): Survey findings from the genomic medicine communities

Klein CJ, Gong L, Caudle KE, Naik H, Empey PE, Hoffman JM, Scherer S, Iwuchukwu OF, Gregornik D, Monte AA, Swen JJ, Scott SA, Whirl-Carrillo M, Klein TE.

Genet Med. 2025 Oct;27(10):101529. DOI: 10.1016/j.gim.2025.101529. PubMed PMID: 40662343.

2025 | Jul 1

CYP2D6 phenotypes and emergency department visits among patients receiving opioid treatment

Nahid NA, McDonough CW, Wei Y-J, Gong Y, Empey PE, Haddad A, Fillingim RB, Johnson JA.

JAMA Netw Open. 2025 Jul 1;8(7):e2523543. DOI: 10.1001/jamanetworkopen.2025.23543. PMID: 40720122.

2025 | Jun 4

Progress in pharmacogenomics implementation in the united states: barrier erosion and remaining challenges

Smith DM, Douglas MP, Aquilante CL, Deverka PA, Devine B, Dunnenberger HM, Empey PE, Hertz DL, Monte AA, Moyer AM, Patel JN, Pratt VM, Saulsberry L, Scott SA, Voora D, Woodahl EL, Whirl-Carrillo 25 M, Oni-Orisan A, Pharmacogenomics Global Research Network (PGRN) Publications Committee

Clin Pharmacol Ther. 2025 Oct;118(4):778-789. DOI: 10.1002/cpt.3736. PMID: 40468601.

2025 | May 16

Pharmacogenomics education among professional societies: assessing practices and future needs

Bailey SL, Messersmith D, Empey PE.

Pharmacogenomics. 2025 Feb-Mar;26(3-4):81-87. DOI: 10.1080/14622416.2025.2502316. PMID: 40375817.

2025 | Jan 23

Pharmacogenetics: Opportunities for the All of Us Research Program and other large data sets to advance the field

Empey PE, Karnes JH, Johnson JA.

Annu Rev Pharmacol Toxicol. 2025 Jan;65(1):111-130. DOI: 10.1146/annurev-pharmtox-061724-080718. PMID: 39847465.