News & Publications – Page 2 – Pittsburgh Pharmacogenomics

2025

2025 | Jan 14

When patients present with direct-to-consumer pharmacogenomic test results

Donnelly RS, Ayoubieh H, Kudron EL, Mills M, Weiler T, Empey PE, Direct-to-Consumer Genetic Testing Project Group of the National Human Genome Research Institute Inter-Society Coordinating Committee for Practitioner Education in Genomics.

Mayo Clin Proc. 2025 Feb;100(2):197-203. DOI: 10.1016/j.mayocp.2024.10.016. PMID: 39818680.

2025 | Jan 3

Integrating pharmacogenomics into the broader construct of genomic medicine: Efforts by the ClinGen Pharmacogenomics Working Group (PGxWG)

Gong L, Klein CJ, Caudle KE, Moyer AM, Scott SA, Whirl-Carrillo M, Klein TE, ClinGen Pharmacogenomics Working Group (PGxWG).

Clin Chem. 2025 Jan 3;71(1):36-44. DOI: 10.1093/clinchem/hvae181. PMID: 39749515.

2024

2024 | Dec 26

Longitudinal pharmacogenomic learning for student pharmacists

LeCompte K, Coons JC, Empey E, Berenbrok LA.

Curr Pharm Teach Learn. 2025 Mar;17(3):102189. DOI: 10.1016/j.cptl.2024.102189. PMID: 39729765.

2024 | Aug 1

Genetic determinants of response to P2Y12 inhibitors and clinical implications

Cavallari LH, Coons JC.

Interv Cardiol Clin. 2024 Oct;13(4):469-481. DOI: 10.1016/j.iccl.2024.06.002. PMID: 39245547.

2024 | Jun 14

Frequency of pharmacogenomic variation and medication exposures among All of Us participants

Haddad A, Radhakrishnan A, McGee S, Smith JD, Karnes JH, Venner E, Wheeler MM, Patterson K, Walker K, Kalra D, Kalla SE, Wang Q, Gibbs RA, Jarvik GP, Sanchez J, Musick A, Ramirez AH, Denny JC, Empey PE.

medRxiv [Preprint]. 2024 Jun 13:2024.06.12.24304664. doi: 10.1101/2024.06.12.24304664. PMID: 38946996

2024 | May 20

Empowering personalized pharmacogenomics with generative AI solutions

Murugan M, Yuan B, Venner E, Ballantyne CM, Robinson KM, Coons JC, Wang L, Empey PE, Gibbs RA.

J Am Med Inform Assoc. 2024 May 20;31(6):1356-1366. DOI: 10.1093/jamia/ocae039. PMID: 38447590.

2023

2023 | Jul 11

Clinical utility of pharmacogenomics in the management of pulmonary arterial hypertension: current perspectives

Coons JC, Empey PE.

Pharmgenomics Pers Med. 2023 Jul 11:16:729-737. DOI: 10.2147/PGPM.S361222. PMID: 37457231.

2022

2022 | Dec 12

Antiplatelet therapy and bleeding outcomes with CYP2C19 genotyping

Coons JC, Stevenson JM, Patel A, Smith AJC, Prebehalla L, Empey PE.

J Cardiovasc Pharmacol Ther. 2022 Jan-Dec:27:10742484221143246. DOI: 10.1177/10742484221143246. PMID: 36503270.

2022 | Nov 9

Evaluation of potential racial disparities in CYP2C19-guided P2Y12 inhibitor prescribing after percutaneous coronary intervention

Cavallari LH, Limdi NA, Beitelshees AL, Lee JC, Duarte JD, Franchi F, Tuteja S, Giri J, Empey PE, Kreutz RP, Skaar TC, Allen JM, Coons JC, Gong Y, McDonough CW, Stevenson JM, Thomas CD, Johnson JA, Stouffer GA, Angiolillo DJ, Lee ACR.

Clin Pharmacol Ther. 2023 Mar;113(3):615-623. DOI: 10.1002/cpt.2776. PMID: 36306392.

2022 | Apr 1

Pharmacists leading the way to precision medicine: Updates to the core pharmacist competencies in genomics

Gammal RS, Lee YM, Petry NJ, Iwuchukwu O, Hoffman JM, Kisor DF, Empey PE

Am J Pharm Educ. 2022 Apr;86(4):8634. PMID: 34301570. doi: 10.5688/ajpe8634